Send Message

Nature and Forms of Phospholipases

Phospholipases are lipolytic enzymes that break down particular ester linkages in phospholipid substrates to produce fatty acids and lipophilic compounds. Phospholipases are widely distributed in nature and have a wide range of functions, from producing aggression in snake venom to signal transduction, the synthesis of lipid mediators, and the digestion of metabolites in humans. The structure, function, regulation, and mechanism of action of phospholipases vary widely. Over the past few decades, there have been enormous advancements in our understanding of the structure and operation of phospholipases.