Brucellosis is a common zoonotic illness worldwide. It mainly affects the reproductive part of cattle, which make them sterile and ultimately cause death. The disease may be transmitted directly from cattles to human through the ingestion of raw or unpasteurized milk and by unhygienic practices. Several diagnostic tools are available to screen the disease and then appropriate antibiotic treatments are administered. The lack of knowledge, awareness and pactices related to brucellosis among cattle keepers are the main reason to accelerate the transmission of the disease. The disease can be prevented by the proper education, mass vaccination and isolation/ slaughtering of infected cattles.