In aquaculture, antibiotics are utilized to stimulate growth. Diverse antibiotic classes, including aminoglycosides, quinolones, sulfonamides, tetracyclines, macrolides, chloramphenicols, nitrofurans, lincosamides, and polymyxins, are used in aquaculture. The "antibiotic resistance problem" is the term used to describe how antibiotics are being misused and abused, along with the appearance and spread of bacteria resistant to antibiotics and resistance genes. Antimicrobial substances either eliminate bacteria (bactericidal) or stop their growth (bacterio-static).